The best HIPAA-compliant analytics platform for healthcare in 2026 is one that keeps PHI inside your infrastructure, connects to your data without requiring a warehouse, and runs AI locally. Knowi is the only platform that does all three: private AI with no external LLM calls, native connectivity to SQL, NoSQL, and API sources without ETL, and on-premises deployment. Tableau, Power BI, Qlik Sense, and six other platforms are evaluated below with their healthcare-specific strengths and limitations. For compliance fundamentals, see What is HIPAA-compliant analytics? Learn more about running AI on patient data without third-party LLMs.
TL;DR
- Only one platform offers on-premises deployment, private AI (no external LLM calls), and native connectivity to SQL, NoSQL, and APIs without ETL: Knowi. Qlik Sense offers on-prem with limited local AI (associative engine only).
- Cloud-only platforms like Domo and ThoughtSpot cannot keep PHI on your infrastructure, which disqualifies them for many health systems.
- The healthcare analytics market is projected to reach $166.65 billion by 2030, growing at 24.6% CAGR, according to MarketsandMarkets.
- No general-purpose BI tool won the KLAS 2025 Best in Healthcare Data and Analytics ranking. Healthcare-specific vendors (Dimensional Insight, Innovaccer, Epic) dominate.
- Power BI raised prices 40% in April 2025, and its AI Copilot requires Fabric F64 capacity at additional cost.
- Sisense experienced a CISA-level security breach in April 2024 that exposed customer credentials, SSL certificates, and access tokens, affecting healthcare customers including Philips Healthcare.
- Every platform in this comparison connects to EHR data through intermediate layers. None have native FHIR connectors built into the BI tool itself.
- Signing a BAA is not enough. Blue Shield of California exposed 4.7 million patient records through a misconfigured Google Analytics implementation despite having compliance agreements in place.
Table of Contents
How We Evaluated These Platforms
We evaluated nine analytics platforms across the criteria that matter most for healthcare: HIPAA compliance infrastructure (BAA, SOC 2, HITRUST, on-premises deployment), AI data processing location (does PHI leave your environment?), data source connectivity (can you query EHR databases directly or do you need a warehouse first?), and total cost of ownership (does the platform require a warehouse, ETL, or AI add-ons to function?).
This is not a general BI comparison. It is specifically about which platforms can handle protected health information without creating compliance risk. If you need a platform that works with clinical, financial, and operational healthcare data, this guide covers what matters.
Healthcare Analytics Platform Comparison Table
| Platform | Signs BAA | On-Prem Deployment | Private AI (No External LLM) | Connects Without ETL/Warehouse | Embedded Analytics | Healthcare Fit |
|---|---|---|---|---|---|---|
| Knowi | Yes | Yes (Docker, Kubernetes) | Yes, full NLQ and document AI run locally | Yes, SQL + NoSQL + REST APIs natively | Full white-label, multi-tenant, embeds AI | Built for healthcare: private AI, any data source without ETL, on-prem deployment |
| Tableau | Yes | Yes (Tableau Server) | No, AI routes through Salesforce Einstein | No, requires data warehouse | Limited white-label, no native multi-tenant | Strong visualization, but AI sends data externally and requires warehouse |
| Power BI | Yes (default) | Yes (Report Server, limited features) | No, Copilot runs on Azure OpenAI | No, requires ETL and flattening | Available via Azure, limited white-label | Microsoft ecosystem fit, but AI requires expensive Fabric tier and no NoSQL support |
| Qlik Sense | Yes | Yes (Windows, Kubernetes) | Partial, associative engine is local but advanced AI is cloud | Limited, requires connectors | Available, not primary focus | HITRUST certified, but steep learning curve and complex cloud PHI setup |
| Domo | Yes (enterprise only) | No, cloud-only | No, AI Pro uses external APIs | Limited, requires connectors | Domo Everywhere, multi-tenant | Cloud-only disqualifies for on-prem PHI requirements |
| Sisense | Yes (with exclusions) | Yes (self-hosted) | No, uses external LLMs | No, requires ElastiCube modeling | Strong, built for embedding | Strong embedding, but CISA breach in 2024 and BAA excludes third-party services |
| ThoughtSpot | Yes | No, cloud-only (on-prem deprecated) | No, uses cloud LLM APIs | No, all data must be warehoused | TypeScript SDK, consumption pricing | Cloud-only, requires warehouse, no healthcare-specific features |
| Looker | Yes (with exclusions) | Customer-managed only | No, Gemini runs on Google Cloud | No, requires LookML modeling | Strong API, requires LookML | Google Cloud lock-in, LookML modeling required, BAA may exclude AI features |
| Metabase | No | Yes (open source, self-hosted) | No, Metabot likely uses external APIs | Basic MongoDB driver only | Limited, watermark on free tier | No BAA, no compliance certs, not healthcare-ready without significant DevOps |
Detailed Platform Analysis
Knowi
Knowi connects natively to MongoDB, Elasticsearch, REST APIs (including FHIR endpoints), and 30+ other sources without ETL. For healthcare organizations with clinical data in document databases or EHR APIs, this eliminates the data warehouse requirement that every other platform in this list imposes.
Knowi is the only analytics platform where the AI engine runs entirely inside your deployment. Natural language queries, anomaly detection, and document AI all process data locally, with no API calls to OpenAI, Azure, or any external service. This makes it the strongest option for healthcare organizations that cannot send PHI outside their infrastructure.
- HIPAA: Signs BAA, SOC 2 Type II certified, on-premises deployment via Docker or Kubernetes
- AI: NLQ works across all connected data sources (not limited to one dashboard). Document AI processes PDFs, clinical notes, and reports with source attribution. All AI runs locally.
- Embedded: Full white-label with custom branding, multi-tenant with row-level and dataset-level security, embeds AI and NLQ into third-party applications
- Limitations: No HITRUST certification (SOC 2 only).
Best for: Healthcare organizations with data in MongoDB, Elasticsearch, or REST APIs that need AI analytics without sending PHI to external services. Health IT companies embedding analytics into patient portals or clinical platforms.
Tableau
Tableau (Salesforce) is the most widely recognized BI platform and offers strong HIPAA compliance through both Tableau Cloud (with BAA) and Tableau Server (on-premises). Its visualization capabilities are the strongest in this comparison.
The limitation for healthcare is AI. Tableau’s AI features (Tableau GPT, Pulse) route through Salesforce’s Einstein platform, which means query data leaves your infrastructure. The new Tableau+ premium tier is required for full AI features, and pricing is not public.
- HIPAA: Signs BAA, SOC 2 Type II, on-premises via Tableau Server, Tableau Cloud on Hyperforce for enhanced data residency
- AI: Tableau GPT and Pulse for natural language insights. AI processing happens in Salesforce cloud. Not available for air-gapped environments.
- Embedded: REST API integrations, but no native multi-tenant support. White-labeling is limited. Embedding adds significant licensing cost.
- Limitations: No native NoSQL support. Requires data extraction to a warehouse. AI features process data externally. Per-user pricing is expensive at scale.
Best for: Healthcare organizations that prioritize interactive data visualization and already have a data warehouse. Not ideal if you need AI that stays local or embedded analytics in a product.
Power BI
Power BI (Microsoft) offers the lowest per-user price and deep integration with the Microsoft ecosystem. For healthcare organizations already using Azure, Microsoft 365, and Teams, Power BI is the natural analytics choice. For a detailed analysis, see Is Power BI HIPAA compliant?
The challenge is AI. Power BI Copilot requires Microsoft Fabric F64 capacity (approximately $0.22/CU/hour), which puts advanced AI out of reach for small and mid-sized healthcare organizations. The on-premises version (Power BI Report Server) has fewer features than the cloud version and does not include Copilot.
- HIPAA: Signs BAA by default (Online Services DPA), SOC 2, HITRUST via Azure, on-premises via Report Server
- AI: Copilot for natural language reports and DAX queries. Q&A being sunset late 2026. AI runs on Azure OpenAI Service (cloud only). Q&A and Copilot only search datasets in the current dashboard.
- Embedded: Power BI Embedded via Azure. Requires separate capacity purchase. Two modes: “App owns data” (customer-facing) and “User owns data” (internal).
- Limitations: No native NoSQL connectivity. AI locked behind expensive Fabric tier. On-prem version is a separate, limited product. Complex licensing (Pro vs PPU vs Premium vs Fabric).
Best for: Healthcare organizations running Microsoft infrastructure that need affordable BI for SQL-based data. Not ideal if your data lives in MongoDB, Elasticsearch, or APIs.
Qlik Sense
Qlik Sense (Thoma Bravo) stands out as one of the few platforms with both HITRUST CSF attestation and HIPAA BAA support. Its unique associative engine lets users explore data relationships without pre-built queries, which is valuable for clinical research and operational analysis.
Qlik claims 2,900+ healthcare organizations use the platform globally. It has dedicated healthcare solution pages, integration with Epic and Cerner workflows, and published clinical and operational dashboard templates.
- HIPAA: Signs BAA, SOC 2 Type II + HITRUST CSF attestation (combined report), on-premises via Windows or Kubernetes, Customer Managed Keys required for PHI in cloud
- AI: Insight Advisor for NLP search, Qlik Predict (AutoML) for no-code ML, associative engine for data exploration. On-prem AI limited to associative engine. Cloud AI uses Qlik’s infrastructure.
- Embedded: Available via APIs and mashup framework. OEM licensing available. Not as embedding-focused as Sisense or Knowi.
- Limitations: Steep learning curve (associative engine is unique). Customer Managed Keys add complexity for cloud PHI. Private equity ownership (Thoma Bravo) creates uncertainty about product direction. On-prem version may lag cloud features. Per-user pricing.
Best for: Large health systems (500+ beds) with dedicated IT teams that are willing to invest in the learning curve. Not ideal for small clinics or teams that need quick deployment.
Domo
Domo signs BAAs and offers a wide connector library (1,000+ pre-built connectors), but it is cloud-only with no on-premises deployment option. For healthcare organizations that require PHI to stay within their own infrastructure, this is a disqualifying limitation. See our full analysis: Is Domo HIPAA compliant?
- HIPAA: Signs BAA (enterprise packages only), SOC 2. No HITRUST. No on-prem or VPC deployment.
- AI: Domo AI (basic tier included) and Domo AI Pro (premium, token-based pricing). AI Pro uses external model APIs.
- Embedded: Domo Everywhere for embedded dashboards with multi-tenant support and Brand Kit customization. Starting at $3,000/month for embedded tier.
- Limitations: Cloud-only (no on-prem). AI Pro uses external APIs (PHI exposure). Consumption-based pricing is unpredictable. Taken private (delisted from NASDAQ 2025), raising long-term stability questions.
Best for: Healthcare operations teams that do not handle PHI directly and need a connector-rich cloud platform. Not suitable for clinical analytics or environments with strict data residency requirements.
Sisense
Sisense was historically a strong choice for embedded healthcare analytics. Its Compose SDK and Fusion Embed platform are purpose-built for OEM scenarios where analytics are embedded directly into patient portals or clinical applications.
However, in April 2024, CISA issued a formal security alert about a Sisense data breach. Attackers accessed Sisense’s GitLab repository, obtained S3 credentials, and exfiltrated several terabytes of customer data including access tokens, email passwords, and SSL certificates. Affected customers included Philips Healthcare, Verizon, and Nasdaq. CISA urged all Sisense customers to reset credentials immediately.
- HIPAA: Signs BAA (excludes third-party services, custom code, uncertified plugins). SOC 2. No HITRUST. Self-hosted option available.
- AI: Sisense Intelligence suite (launched May 2025) with generative AI and natural language queries. Uses external LLMs. AI Agents planned for H1 2026.
- Embedded: Fusion Embed and Compose SDK. Full white-label and multi-tenant. Built for OEM use cases.
- Limitations: CISA-level security breach in 2024. BAA excludes third-party integrations. Ongoing restructuring (layoffs 2023-2024). ElastiCube modeling adds setup time. No native NoSQL. Gartner downgraded to Niche Player in 2025.
Best for: Organizations with strong internal security teams that can manage the risk profile. Healthcare buyers should factor the 2024 breach into vendor risk assessments.
ThoughtSpot
ThoughtSpot pioneered search-based analytics, where users type questions instead of building dashboards. Its Spotter AI and SpotIQ anomaly detection are strong, but the platform is cloud-only (on-prem was deprecated) and requires all data to live in a supported cloud warehouse.
- HIPAA: Signs BAA, SOC 2. No HITRUST. Cloud-only (no on-prem option).
- AI: Spotter for NLP queries, SpotIQ for automated anomaly detection. NLQ requires a pre-built semantic layer (weeks to configure). Cloud-based AI processing.
- Embedded: TypeScript SDK with white-label support. Multi-tenancy on Enterprise plan only. Consumption-based pricing for embedded.
- Limitations: Cloud-only. All data must be warehoused first. NLQ only works on modeled data. No native NoSQL, API, or FHIR connectivity. Consumption-based pricing unpredictable. No healthcare-specific templates or integrations.
Best for: Well-funded organizations that already use Snowflake or BigQuery and want search-first analytics for business users. The cost and cloud-only architecture make it impractical for most healthcare organizations.
Looker
Looker (Google Cloud) offers a strong semantic layer through LookML and access to Gemini AI. Google Cloud has HITRUST certification and signs BAAs for Looker Hosted Deployments. However, Looker requires LookML expertise for setup, and its AI features (Gemini) process data in Google Cloud.
- HIPAA: Signs BAA (excludes beta features and third-party services). SOC 2 and HITRUST via Google Cloud. Customer-managed deployment available.
- AI: Gemini in Looker for conversational analytics and LookML generation. AI processes data in Google Cloud. Gemini features currently in preview (may move to paid tier).
- Embedded: Strong Looker API. Multi-tenant via LookML row-level security. White-label with custom themes.
- Limitations: LookML modeling layer required (steep learning curve). Gemini processes PHI in Google Cloud. Product naming confusion (Looker vs Looker Studio vs Looker Studio Pro). BAA may not cover Gemini features in preview.
Best for: Healthcare organizations already on Google Cloud with teams that can learn LookML. Not ideal for multi-cloud or on-prem environments.
Metabase
Metabase is an open-source BI tool that is free to self-host. It is the most affordable option in this comparison. However, Metabase does not sign BAAs, has no SOC 2 or HITRUST certification, and its cloud version is explicitly not recommended for HIPAA-regulated organizations.
- HIPAA: No BAA. No SOC 2. No HITRUST. Self-hosting is the only path to HIPAA compliance, and the organization bears full responsibility for infrastructure security.
- AI: Metabot for natural language queries and SQL generation. Limited compared to enterprise platforms. AI processing location unclear.
- Embedded: Static embedding on open-source (with “Powered by Metabase” watermark). Interactive embedding on Pro/Enterprise. Limited multi-tenancy.
- Limitations: No BAA, no compliance certifications. No healthcare templates or EHR integrations. Open-source requires significant DevOps for production HIPAA deployment. No anomaly detection, no document AI, no cross-source joining.
Best for: Small clinics or research teams with DevOps capability that need basic SQL dashboards and can manage their own HIPAA compliance. Not suitable for organizations that need vendor-backed compliance guarantees.
Why a BAA Alone Does Not Make a Platform HIPAA-Compliant
Every platform in this comparison except Metabase signs a BAA. But a BAA is a legal contract, not a technical safeguard. It creates liability after a breach. It does not prevent one.
The Blue Shield of California incident demonstrates this. Blue Shield had compliance agreements with Google, yet a misconfigured Google Analytics implementation exposed 4.7 million patient records to Google Ads over a three-year period. The BAA did not stop PHI from flowing to an advertising platform.
When evaluating platforms, ask these questions beyond the BAA:
- Where does AI processing happen? If the platform sends queries to OpenAI, Azure OpenAI, or Gemini, your data leaves your infrastructure even if the dashboard stays local.
- What does the BAA exclude? Sisense’s BAA excludes third-party services, custom code, and uncertified plugins. Looker’s BAA excludes beta features (which may include Gemini AI).
- Can you deploy on-premises? Cloud-only platforms (Domo, ThoughtSpot) mean PHI lives on the vendor’s infrastructure.
- What happens if you disconnect from the internet? If AI features stop working, they depend on external services.
Which Platform Should You Choose?
For most healthcare organizations: Knowi
If you need analytics that work across multiple healthcare data sources without building a warehouse, keep AI processing inside your infrastructure, and deploy on-premises or in your VPC, Knowi is the most complete option. It is the only platform in this comparison that checks every box: private AI, native connectivity to SQL + NoSQL + APIs without ETL, on-premises deployment, and embedded analytics with white-label. See a healthcare analytics demo.
If you are locked into Microsoft: Power BI
Healthcare organizations already running Azure, Microsoft 365, and Teams may find Power BI is the path of least resistance for SQL-based data. Be aware that AI (Copilot) requires expensive Fabric capacity, the on-prem version has limited features, and there is no native NoSQL or API connectivity.
If you already have a data warehouse and Tableau expertise: Tableau
Tableau’s visualization is the strongest in this comparison, but it requires your data to already be in a warehouse. AI features route through Salesforce’s cloud. Per-user licensing scales quickly. For a detailed HIPAA analysis, see Is Tableau HIPAA compliant?
If HITRUST certification is a hard requirement: Qlik Sense
Qlik is one of the few BI platforms with HITRUST CSF attestation. The tradeoff is a steep learning curve, complex cloud PHI setup (Customer Managed Keys required), and limited embedding capabilities.
Avoid for healthcare:
Domo and ThoughtSpot are cloud-only with no on-premises option. Metabase does not sign BAAs and has no compliance certifications. Sisense had a CISA-level security breach in April 2024 that exposed healthcare customer data. Looker requires Google Cloud lock-in and LookML expertise.
Frequently Asked Questions
What is the best HIPAA-compliant analytics platform for healthcare?
It depends on your data infrastructure. Knowi is best for organizations with NoSQL data (MongoDB, Elasticsearch) and those that need AI to run inside their own environment. Power BI is best for Microsoft-native organizations with SQL data. Qlik Sense is best for large health systems that need HITRUST certification. Tableau is best for visualization-focused teams with existing data warehouses.
Which analytics platforms offer on-premises deployment for HIPAA?
Knowi (Docker, Kubernetes), Tableau (Tableau Server), Power BI (Report Server with limited features), Qlik Sense (Windows, Kubernetes), Sisense (self-hosted), and Metabase (open source, self-hosted). Domo and ThoughtSpot are cloud-only and do not offer on-premises deployment.
Do any analytics platforms keep AI processing inside your infrastructure?
Only Knowi runs its full AI engine (natural language queries, document AI, anomaly detection) entirely inside the customer’s deployment with no calls to external LLM services. Qlik’s associative engine runs locally on-premises, but its advanced AI features use cloud processing. Every other platform in this comparison sends AI queries to external services (Azure OpenAI, Salesforce Einstein, Google Gemini).
Is Tableau HIPAA compliant?
Yes. Tableau Cloud is HIPAA compliant and Salesforce signs BAAs. Tableau Server can be deployed on-premises for full data control. However, Tableau’s AI features (Tableau GPT, Pulse) route through Salesforce’s cloud infrastructure, meaning AI-related data processing happens outside your environment.
Is Power BI HIPAA compliant?
Yes. Microsoft includes HIPAA BAA coverage by default through the Online Services Data Protection Addendum. Power BI Report Server offers on-premises deployment. Microsoft Fabric is HIPAA compliant as of 2024. The limitation is that Copilot AI requires Fabric F64 capacity and processes data on Azure OpenAI, which adds cost and moves AI processing to Microsoft’s cloud.
What happened with the Sisense security breach?
In April 2024, CISA issued a formal alert about a Sisense data compromise. Attackers accessed Sisense’s GitLab repository, obtained Amazon S3 credentials, and exfiltrated several terabytes of customer data including access tokens, email passwords, and SSL certificates. Affected customers included Philips Healthcare, Verizon, and Nasdaq. CISA urged all Sisense customers to reset credentials for all services accessed through the platform.
Can these platforms connect to Epic or Cerner EHR systems?
No platform in this comparison has a native, purpose-built connector for Epic or Cerner. All connect to EHR data through intermediate layers: data warehouses (Clarity/Caboodle for Epic), REST APIs (FHIR endpoints), or Azure/Google healthcare middleware services. Knowi connects to FHIR endpoints via its native REST API connector. Power BI connects via Azure Health Data Services. Looker connects via Google Cloud Healthcare API.